Last weekend I tried some Vando reeds on bass clarinet, after having played Légères for years. I have to say cane reeds sound much better to my ears on bass, but I have a pretty strong (allergic) reaction to them. Within 30 minutes I develop a burning feeling, and small blisters on my lip and where the skin touches the reed. If I keep playing my lip will eventually split altogether. I've tried soaking, sanding and all kinds of other reed treatment on various brands. Nothing seems to work. Is there some component in cane that can cause this?