Yeah, probably because you have spit on your reed just inside your mpc.
The only "solution" I know of is just to suck hard on your mpc to try to bring the spittle out and into your mouth.
A couple of days ago, for some crazy reason I had this problem bad. I even changed mpcs twice because I thought it might have had something to do with it - as suspected it didn't. So I blew, and sucked, and I hated my sound and got so frustrated I just quit for the day.
You should also take care that you don't have too much saliva in your mouth, don't suck on any lemons or Daiquiris before playing.
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