In short: no, unless you injure your hands very badly eg severed tendon or lose the end of a finger etc. Certainly your finger tips being calloused etc will make little or no difference. You may find you have to put less effort/tension/strength into the use of your hands in playing the sax than you do in your work.Is working really hard on buildings (handling heavy buckets, shovel, trowel) will eliminate me from being a sax player?
Good advice. Cramps are a big problem associated with dehydration and the lack of essential minerals. I once had terrible trouble with finger cramps when I rushed to a gig after shovelling all day. I needed to drink a couple of litres of water before I could carry on. Essential minerals like magnesium, potassium and calcium that often come in vitamin supplements can stop painful muscle spasms and cramps, especially at night after a hard day's physical work.drink a lot of water and make sure you stretch