when I was in school practicing a lot, I got common scales in hand memory; but one thing I should have worked harder at was getting the chord extensions to be 2nd nature. Ammons and of course Bird danced with those all day long. when playing in F, I can easily work in notes not in the scale. When playing in F# there is a tendency to stay in the safe zone. One can play any note really, but it has to be in the right place. lolFingering patterns are different on piano too. Beginners often think C is the easiest key because the mind only has to think "white keys" but actually B major fits the (right) hand the best for running a scale up and down many octaves and is easier to get faster on, imo, so yeah-- familiarity is all it is.